1. To clear of accusation, blame, suspicion, or doubt with supporting arguments or proof: 'Our society permits people to sue for libel so that they may vindicate their reputations'(Irving R. Kaufman).
2. To provide justification or support for: vindicate one's claim.
3.To justify or prove the worth of, especially in light of later developments.
4. To defend, maintain, or insist on the recognition of [one's rights] for example.
5. To exact revenge for; avenge.